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Synthesis of 3-(3-Methyl-1-aryl-1H-pyrazol-5-yl)-2H-2-chromen-2-one Derivatives via a One-Pot, Three-Component Reaction
Version 2 2014-05-14, 15:49
Version 1 2014-05-14, 15:49
journal contribution
posted on 2014-05-14, 15:49 authored by Abdolali Alizadeh, Rashid GhanbaripourAn efficient synthesis of 3-(3-methyl-1-aryl-1H-pyrazol-5-yl)-2H-2-chromen-2-one derivatives by the reaction of salicylaldehydes, 4-hydroxy-6-methyl-2H-pyran-2-one, and arylhydrazine in acetonitrile under reflux condition and in the presence of piperidine is reported. This three-component reaction has some advantages such as ease of handling, good yields, and easy purification. All structures were confirmed by infrared, mass, 1H NMR, and 13C NMR spectroscopy.