gpss_a_1311332_sm5022.docx (10.11 MB)
0/0

The synthesis of new fluorinated or nonfluorinated sugar phosphonates and phosphoramidates as building blocks in the synthesis of modified hyaluronic acid subunits

Download (10.11 MB)
journal contribution
posted on 25.05.2017 by Katarzyna Koroniak-Szejn, Joanna Tomaszewska, Henryk Koroniak

The synthesis of several new fluorinated or nonfluorinated sugar phosphonates and phosphoramidates as building blocks for the synthesis of modified hyaluronic acid subunits is described. These compounds were prepared from d-glucose and d-glucosamine hydrochloride. The syntheses of phosphonates and phosphoramidates are based on arbuzov and staudinger reactions. The products were fully characterized by 1H, 13C, 19F, 31P NMR, and ESI MS spectroscopy.

History

Licence

Exports