gnpl_a_998216_sm4353.doc (3.9 MB)
0/0

Triglyceride accumulation inhibitory effects of new chromone glycosides from Drynaria fortunei

Download (0 kB)
journal contribution
posted on 04.08.2015 by Lifeng Han, Fang Zheng, Yi Zhang, Erwei Liu, Wei Li, Minghui Xia, Tao Wang, Xiumei Gao

Two new chromone glycosides, drynachromosides C (1) and D (2), along with five known chromones (37), were isolated from the rhizomes of Drynaria fortunei. The structures of the two new compounds were elucidated on the basis of physico-chemical property and spectroscopic data. Triglyceride (TG) accumulation inhibitory effects of the obtained chromones on 3T3-L1 cells were investigated. The results showed that 1, 2 and 5 exhibited inhibitory activity on TG accumulation. Effects of compounds 1 and 2 on mRNA expression of PPARγ, C/EBPα and aP2 in 3T3-L1 cells were also investigated.

History

Licence

Exports