Two new bicyclic sesquiterpenes from the stems of Kadsura heteroclita

Su, Wei; Zhao, Jian-Ping; Hu, Jian; Yang, Min; Jacob, Melissa; Cai, Xiong; Zeng, Rong; Chen, Sheng-Huang; Huang, Hui-Yong; Khan, Ikhlas; Guo, De-An; Wang, Wei

doi:10.6084/m9.figshare.1009735.v2

gnpl_a_910664_sm6350.doc (8.14 MB)

Two new bicyclic sesquiterpenes from the stems of Kadsura heteroclita

Version 2 2014-07-01, 07:25

Version 1 2014-07-01, 07:25

journal contribution

posted on 2014-07-01, 07:25 authored by Wei Su, Jian-Ping Zhao, Jian Hu, Min Yang, Melissa Jacob, Xiong Cai, Rong Zeng, Sheng-Huang Chen, Hui-Yong Huang, Ikhlas Khan, De-An Guo, Wei Wang

Two new bicyclic sesquiterpenes, namely 6α,9α-dihydroxycadinan-4-en-3-one (1) and guai-3-en-10α-ol (2), together with one known sesquiterpene were isolated from the stems of Kadsura heteroclita, which is a Tujia ethnomedicine called ‘Xue Tong’. Their structures were elucidated by using spectroscopic analyses and by comparing the NMR data with those reported previously.