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Two new cephalochromin derivative from the Alternaria sp. ZG22

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journal contribution
posted on 2019-12-14, 14:09 authored by Xin-Ming Song, Xue-Ming Zhou, Ya-Ling Li, Li-Bing Huang, Cai-Cui Chen, Yan Gao, Lin He, Xiao-qun Mao, Bing Chen, Jing-Wen Liu, Hui-Jie Liu, Xiao-Ping Song, Chang-Ri Han

Two new cephalochromin derivatives, prenylcephalochromin A (1), prenylcephalochromin B (2), along with cephalochromin (3) were isolated from the Alternaria sp. ZG22 obtained from a Dasymaschalon rostratum collected from the Hainan. The structures of two new compounds were elucidated by comprehensive spectroscopic methods. Compounds 1-3 showed α-glucosidase inhibitory activity.

Funding

This work was supported by the Key Research and Development Project of Hainan Province [grant number ZDYF2018164]; the Scientific research project of Hainan province colleges and universities [grant number Hnky2017-87]; the Undergraduate Innovation and Entrepreneurship Training Program [grant numbers cxcyxj2018008, cxcyxj2018010]; the Natural Science Foundation of Hainan Province[grant number 218QN234]; the Innovative Research Team Project of Ministry [grant number IRT-16R19]; the Special projects of the central government for the development of local science and technology [grant number ZY2018HN07].

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    Alternaria sp.cephalochromin derivativesα-glucosidase inhibitory activity

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