gnpl_a_1591397_sm3723.pdf (1.35 MB)
Two new compounds from the heartwood of Dalbergia melanoxylon
journal contribution
posted on 2019-04-16, 12:19 authored by Shuai Lin, Rong-Hua Liu, Guang-Qiang Ma, Dan-Yi Mei, Feng Shao, Lan-Ying ChenA new neoflavonoid, named S(+)-3′-hydroxy-4′,2,4,5-tetramethoxydalbergiquinol (1), and a new benzofuran, named (2S,3S)-5-hydroxy-6-methoxy-3-methyl-2-(4′-hydroxyphenyl)-2,3dihydrobenzofuran (4), together with two known neoflavonoids, were isolated from the heartwood of Dalbergia melanoxylon. Their structures were elucidated by a combination of spectroscopic methods and comparison with the literature. Compounds 1–4 were evaluated for inhibitory activity against Staphylococcus aureus ATCC 25923, Escherichia coli ATCC 6538, Salmonella enteri CMCC 50041 and Candida albicans ATCC 289065, which all exhibited inactive or weak activity.