Two new compounds from the marine sponge derived fungus Penicillium chrysogenum

Han, Xiao; Li, Pinglin; Luo, Xiangchao; Qiao, Dan; Tang, Xuli; Li, Guoqiang

doi:10.6084/m9.figshare.7964690.v1

gnpl_a_1598994_sm1224.pdf (819.1 kB)

Two new compounds from the marine sponge derived fungus Penicillium chrysogenum

journal contribution

posted on 2019-04-08, 11:09 authored by Xiao Han, Pinglin Li, Xiangchao Luo, Dan Qiao, Xuli Tang, Guoqiang Li

Two new compounds (1 and 2) were isolated from the marine sponge derived fungus Penicillium chrysogenum by using various column chromatography techniques. Their structures were elucidated by extensive analysis of spectroscopic data and quantum chemical calculation. Compound 1 exhibited moderate activity against PTP1B with 2.95 ± 0.97% at the concentration of 30 μmol·L⁻¹.