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Construction, Properties, and Analysis of Group-Orthogonal Supersaturated Designs

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Version 2 2021-09-29, 16:44
Version 1 2019-08-13, 19:15
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posted on 2021-09-29, 16:44 authored by Bradley Jones, Ryan Lekivetz, Dibyen Majumdar, Christopher J. Nachtsheim, Jonathan W. Stallrich

In this article, we propose a new method for constructing supersaturated designs that is based on the Kronecker product of two carefully chosen matrices. The construction method leads to a partitioning of the factors of the design such that the factors within a group are correlated to the others within the same group, but are orthogonal to any factor in any other group. We refer to the resulting designs as group-orthogonal supersaturated designs. We leverage this group structure to obtain an unbiased estimate of the error variance, and to develop an effective, design-based model selection procedure. Simulation results show that the use of these designs, in conjunction with our model selection procedure enables the identification of larger numbers of active main effects than have previously been reported for supersaturated designs. The designs can also be used in group screening; however, unlike previous group-screening procedures, with our designs, main effects in a group are not confounded. Supplementary materials for this article are available online.

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