Genetic polymorphisms of very important pharmacogene variants in the Chinese Lisu population - supplementary material

  

Supplementary Figure 1 The genotype frequency distribution of rs20417 (PTGS2) among 27 populations. The value of the Y axis represents the genotype frequency (%). 

  

Supplementary Figure 2 The genotype frequency distribution of rs776746 (CYP3A5) among 27 populations. The value of the Y axis represents the genotype frequency (%). 

  

Supplementary Figure 3 The genotype frequency distribution of rs1805123 (KCNH2) among 27 populations. The value of the Y axis represents the genotype frequency (%). 

  

Supplementary Figure 4 The genotype frequency distribution of rs2115819 (ALOX5) among 27 populations. The value of the Y axis represents the genotype frequency (%). 

  

Supplementary Figure 5 The genotype frequency distribution of rs4291 (ACE) among 27 populations. The value of the Y axis represents the genotype frequency (%). 

  

Supplementary Figure 6 The genotype frequency distribution of rs1051298 (SLC19A1) among 27 populations. The value of the Y axis represents the genotype frequency (%). 

  

Supplementary Figure 7 The genotype frequency distribution of rs1065852 (CYP2D6) among 27 populations. The value of the Y axis represents the genotype frequency (%). 

  

Supplementary Table 1 PCR primers for the selected variants

  

Supplementary Table 2 The Genotype Distribution Difference between Lisu and 26 other populations with Bonferroni’s multiple correction

  

Supplementary Table 3 The genotype and allele frequency distribution of seven SNPs among 27 populations

  

Supplementary Table 4 Clinical Annotations of selected SNPs

  

Supplementary Table 5 Significant Difference SNP and Drug Related Information