Potential of fluorescent nanoprobe in diagnosis and treatment of Alzheimer’s disease Supplementary figures nnm-2022-0022

Alzheimer’s disease (AD) is well known for its insidious nature, slow progression and high incidence as

a neurodegenerative disease. In the past, diagnosis of AD mainly depended on analysis of a patient’s

cognitive ability and behavior. Without a unified standard for analysis methods, this is prone to produce

incorrect diagnoses. Currently, definitive diagnosis mainly relies on histopathological examination.

Because of the advantages of precision, noninvasiveness, low toxicity and high spatiotemporal resolution,

fluorescent nanoprobes are suitable for the early diagnosis of AD. This review summarizes the research

progress of different kinds of fluorescent nanoprobes for AD diagnosis and therapy in recent years and

provides an outlook on the development prospects of fluorescent nanoprobes.