Somatic
mutation and copy number variation events in TNBC subgroups
(A)
Waterfall plots corresponding to the distributions of the top 25 most
commonly mutated genes in the two TNBC subtypes.The mutational type
include frame shift del, frame shift ins, in frame del, in frame ins, missense
mutation, multi hit, nonsense mutation and splice site. Each column
represented individual patients. (B) GISTIC plots corresponding to
genomic regions harboring CNVs in the TCGA-TNBC cohort, with gains and losses
being shown in red and blue, respectively, for Group 1 (left) and Group 2
(right).