gnpl_a_1538995_sm6872.pdf (1.65 MB)
A new triterpenoid saponin from Pulsatilla cernua predicted by NMR-based mosaic method
journal contribution
posted on 2018-12-03, 17:03 authored by An-Dong Wang, Ying Bao, Xia Wang, Mei-Chen Li, Xu-Hong Ren, Jian-Yu Liu, Yong-Nan XuA saponin (1) with gypsogenin as aglycone was isolated from the roots of Pulsatilla cernua. The aglycone of compound 1 was considered as gypsogenin which was rarely found in this genus. Its structure was predicted by NMR-based “mosaic” method rapidly, and further confirmed on the basis of spectroscopic data, including 2D NMR spectra and chemical evidence. This work suggested that NMR-based mosaic method is suitable for most of saponins from common species of genus Pulsatilla.