lsyc_a_1499037_sm5254.pdf (4.64 MB)
Enantioselective total syntheses of (−)-clavaminol A and deacetyl (+)-clavaminol H
journal contribution
posted on 2018-08-10, 13:34 authored by Rachana Pandey, Anju Gehlawat, Ranjana Prakash, Satyendra Kumar PandeyAn efficient enantioselective approach to the syntheses of (−)-clavaminol A and deacetyl (+)-clavaminol H is presented, starting from n-decanol. The synthesis features Sharpless asymmetric dihydroxylation (AD), regioselective epoxide formation/opening and α-tosylation as key steps.