gnpl_a_879472_sm5069.doc (2.15 MB)

Microwave-assisted preparation of azachalcones and their N-alkyl derivatives with antimicrobial activities

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journal contribution
posted on 31.03.2014, 10:58 by Asu Usta, Elif Öztürk, Fatih Ş. Beriş

Two new azachalcones were prepared by both Claisen–Schmidt condensation and a simple environmentally trendy microwave-assisted method. Ten new N-alkyl (C6,8,10,12,14)-substituted azachalconium bromides (3ae, 4ae) were prepared from compounds 1 and 2 with corresponding alkyl halides. The antimicrobial activities of all the compounds were tested against Enterococcus faecalis, Yersinia pseudotuberculosis, Pseudomonas aeruginosa, Escherichia coli and Staphylococcus aureus micro-organisms.

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