gpss_a_1119139_sm4680.docx (2.28 MB)
Nano Gd2O3 catalyzed synthesis and anti-oxidant activity of new α-aminophosphonates
journal contribution
posted on 2016-04-29, 15:49 authored by Kandula Madhu Kumar Reddy, Sarva Santhisudha, Gundluru Mohan, Kotha Peddanna, Chippada Appa Rao, Cirandur Suresh ReddyA one pot three-component nano Gd2O3 catalyzed neat reaction of 2-morpholinoethanamine and dimethylphosphite with various salicylaldehydes under microwave irradiation afforded a series of new α-aminophosphonates in high yields. The synthesized compounds were characterized by FT-IR, (1H, 13C, 31P)-NMR, and mass spectral methods. The antioxidant activity of these compounds was evaluated against DPPH, NO, and H2O2 methods and found that the compound Dimethyl (2-hydroxy-5-nitrophenyl) (2-morpholinoethylamino) methylphosphonate (4h) has higher antioxidant activity than the corresponding standards.