lsyc_a_1762092_sm8592.doc (6.09 MB)
Recyclable heterogeneous palladium-catalyzed carbonylative Sonogashira coupling under CO gas-free conditions
Version 2 2020-06-16, 19:58
Version 1 2020-05-07, 14:34
journal contribution
posted on 2020-06-16, 19:58 authored by Zebiao Zhou, Jianying Li, Zhaotao Xu, Mingzhong CaiA convenient, efficient and practical heterogeneous palladium-catalyzed carbonylative Sonogashira coupling of aryl iodides with terminal alkynes under CO gas-free conditions has been developed by using an MCM-41-supported bidentate phosphine palladium acetate complex as catalyst. Here, formic acid was used as the CO source with dicyclohexylcarbodiimide (DCC) as the activator and a wide variety of alkynyl ketones were generated in moderate to high yields. This heterogeneous palladium catalyst can be easily recovered via a simple filtration process and recycled up to 8 times without apparent loss of activity.