gpss_a_1321645_sm1382.docx (1.63 MB)
Synthesis of 4-acetyl-2(3H)-benzothiazolone: Sulfur bioisostere of benzoxazolone allelochemicals
journal contribution
posted on 2017-07-12, 14:23 authored by Mariana S. Gerova, Filip E. Svetoslavov, Boris L. Shivachev, Rositsa P. Nikolova, Ognyan I. PetrovA multi-step methodology for the synthesis of 4-acetyl-2(3H)-benzothiazolone was developed in order to prepare a new biomimetic analogue of benzoxazolone allelochemicals. The compound was prepared from commercially available o-toluidine in 23% overall yield. The structure of 4-acethyl-2(3H)-benzothiazolone was confirmed by NMR spectroscopy and X-ray crystallography.