lsyc_a_1271895_sm2181.docx (4.66 MB)
Synthesis of thienyl-substituted isochromene derivatives through gold-catalyzed tandem heteroarylation/cycloisomerization of ortho-alkynylbenzaldehydes with thiophenes
Version 2 2017-01-27, 14:45
Version 1 2016-12-21, 17:26
journal contribution
posted on 2017-01-27, 14:45 authored by Hongbo Zhu, Xin Meng, Ziping Cao, Guang Chen, Xuejun Sun, Jinmao YouWe describe herein a gold-catalyzed tandem heteroarylation/cycloisomerization reaction of ortho-alkynylbenzaldehydes with thiophenes. By this reaction, a variety of 1-(thiophen-2-yl)-1H-isochromene derivatives can be obtained in good yield.