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Terragines F–G produced by endophytic Bacillus sp. SH-1.2-ROOT-18 from Dendrobium officinale

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posted on 2021-05-05, 09:20 authored by Youjuan Zhu, Shiyang Li, Yichao Kong, Huimin Zhao, Yuanzhuo Hu, Jingyi Meng, Xiabin Chen, Shurong Hou, Xiachang Wang

Two new terragine analogs (12) with special succinimide and aminopentane moieties were isolated from the fermentation broth of Bacillus sp. SH-1.2-ROOT-18, an endophyte previously discovered from the root of Dendrobium officinale. The structures were elucidated base on comprehensive 1 D/2D NMR and MS data analysis. Complete NMR assignments for the first reported naturally occurring metabolite 3 was also provided.

Funding

This research was financially supported by National Key R&D Program (No. 2019YFC1711500), Nature Science Foundation of Jiangsu Higher Education Institutions of China (No. 19KJA180008), Postgraduate Research & Practice Innovation Program of Jiangsu Province (KYCX20_1584) and Jiangsu Provincial "Double Creation Talent Program" (202010528).

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