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Two amide glycosides from Portulaca oleracea L. and its bioactivities

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journal contribution
posted on 05.09.2019, 08:33 by Xilong Liu, Haibo Wu, Xiaojun Tao, Xixiang Ying, Didier Stien

Two novel amide glycosides, named oleraciamide E (1) and oleraciamide F (2), were isolated from the Portulaca oleracea L. Their structures were determined by means of 1D and 2D NMR spectroscopic and UHPLC-ESI-TOF-MS methods. Oleraciamide E (1) exhibited anticholinesterase activity with IC50 values of 52.43 ± 0.33 μM, and presented scavenging activity in 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical quenching assay, with the IC50 values of 24.64 ± 0.33 μM.


This work was supported by the National Natural Science Foundation of China (Grant 81573546).