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New flavonoid glycosides from seeds of Baccharoides anthelmintica

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journal contribution
posted on 2019-03-01, 14:13 authored by Yi Liu, Wen-qiong Wang, Tong Chen, Li-jiang Xuan

Baccharoides anthelmintica is the most popular traditional Uighur medicines used for vitiligo. The chemical investigation of the seeds of B. anthelmintica led to the isolation of three new flavonoid glycosides (Vernosides A-C). Their structures were determined by comprehensive analysis of spectroscopic data including 1D and 2D NMR and HRMS data. Vernosides A-C were evaluated for their effects on tyrosinase activity, Vernoside B can enhance tyrosinase activity.

Funding

This research was supported by a grant from the State Key Laboratory of Drug Research (NO.SIMM1601ZZ-03), the National Natural Science Foundation of China (NO. 81773863, No. 21702219).

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