lsyc_a_1422519_sm0779.docx (1.39 MB)
Palladium-catalyzed facile synthesis of furoquinolinones and furopyridinones
journal contribution
posted on 2018-02-13, 16:45 authored by Tao Guo, Xu-Ning Wei, Hong-Yan Wang, Bing ZhaoThis work is focused on the development of a convenient and efficient approach for the synthesis of furoquinolinones and furopyridinones through palladium-catalyzed cyclization reactions between styrenes and 4-hydroxyquinolinones/4-hydroxypyridinones under air conditions. Studies conducted to evaluate the antitumoral potential of the resulted compounds revealed that some of the obtained furoquinolinones exhibited in vitro antiproliferative activity on human-derived stomach cancer cell lines.