gsch_a_1702194_sm3998.pdf (5.59 MB)
Simple isophthalamides/dipicolineamides as active transmembrane anion transporters
journal contribution
posted on 2019-12-14, 08:15 authored by Giacomo Picci, Israel Carreira-Barral, Daniel Alonso-Carrillo, David Sanz-González, Pablo Fernández-López, María García-Valverde, Claudia Caltagirone, Roberto QuesadaEight N,N´-diarylisophthalamide/dipicolineamide derivatives have been synthesised and fully characterised, both in solution and in the solid state. The transmembrane anion transport properties of these compounds have been studied by chloride-selective electrode and fluorescence experiments. The substitution pattern of the aromatic moieties determines the transport properties of these systems, with those containing electron-withdrawing groups in their structures being the most active ones of the series.